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What is the recommended duration of anticoagulant prophylaxis in DVT?

Asked by Eurona 

The recommendations are as follows:

1. Provoked DVT (with reversible surgical or nonsurgical provoking factor): 3 months

2. Unprovoked isolated distal DVT (has low risk of recurrence): 3 months

3. Unprovoked proximal DVT or PE: Indefinite therapy if D-dimer positive after 1 month after 3 months of therapy or second VTE episode or based on patient preference if no bleeding risk

4. Cancer: Indefinite therapy or until cancer is active

Kearon C, Akl EA. Duration of anticoagulant therapy for deep vein thrombosis and pulmonary embolism. Blood. 2014 Mar 20;123(12):1794-801. doi: 10.1182/blood-2013-12-512681. Epub 2014 Feb 4. PMID: 24497538.